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Title: Dysgammaglobulinemia  
Author: World Heritage Encyclopedia
Language: English
Subject: Hypergammaglobulinemia, Hyper-IgM syndrome type 5, Hyper-IgM syndrome type 3, Adenosine deaminase deficiency, Hyperimmunoglobulin E syndrome
Publisher: World Heritage Encyclopedia


Dysgammaglobulinemia is a type of immune disorder characterized by a reduction in some types of gamma globulins.[3][4]

It is distinguished from hypogammaglobulinemia, which is a reduction in all types of gamma globulins.[5]

Hyper IgM syndrome can be considered a form of dysgammaglobulinemia, because it results from a failure of transformation from IgM production to production of other antibodies, and so the condition can be interpreted as a reduction of the other types.


External links

  • Raif S. Geha et al.: "Hyper Immunoglobulin M Immunodeficiency (Dysgammaglobulinemia)", Journal of Clinical Investigation, 1979 August; 64(2): 385–391, doi:10.1172/JCI109473. Accessed 2009-07-17.
  • Andre Cruchaud et al.: "The site of synthesis of the 19S T-globulins in dysgammaglobulinemia" (1962). Accessed 2009-07-17.

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