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Boettcher cell

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Title: Boettcher cell  
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Boettcher cell

Boettcher cells are a special cell type located in the inner ear.

Boettcher cells are polyhedral cells on the microvilli into the intercellular space.

Because of their structural specialization, Boettcher cells are believed to play a significant role in the function of the cochlea. They demonstrate high levels of calmodulin, and may be involved in mediating Ca2+ regulation and ion transport. Boettcher cells are named after German pathologist Arthur Boettcher (1831-1889).

Nitric oxide synthase is detected abundantly in the cytoplasm of their interdigitations. Their ultrastructure suggests that they perform both secretory and absorptive functions. Panx1 expression has been observed.[2]

References

  1. ^ Kanazawa, A.; Sunami, K.; Takayama, M.; Nishiura, H.; Tokuhara, Y.; Sakamoto, H.; Iguchi, H.; Yamane, H. (Oct 2004). "Probable function of Boettcher cells based on results of morphological study: localization of nitric oxide synthase.". Acta Otolaryngol Suppl (554): 12–6.  
  2. ^ Wang XH, Streeter M, Liu YP, Zhao HB (January 2009). "Identification and characterization of pannexin expression in the mammalian cochlea". J. Comp. Neurol. 512 (3): 336–46.  
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