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BMX (gene)

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BMX (gene)

BMX non-receptor tyrosine kinase
2EKX.
Available structures
PDB Ortholog search: RCSB
Identifiers
2.7.10.2
RNA expression pattern

Cytoplasmic tyrosine-protein kinase BMX is an enzyme that in humans is encoded by the BMX gene.[1][2]

Tyrosine kinases are either receptor molecules, which contain transmembrane and extracellular domains, or nonreceptor proteins, which are located intracellularly. One family of nonreceptor TKs includes the genes TEC (MIM 600583), TXK (MIM 600058), ITK (MIM 186973), and BTK (MIM 300300). All of these proteins are homologs of the Drosophila Src28 TK and contain an SH3 and SH2 domain upstream of the TK domain.[supplied by OMIM][2]

Interactions

BMX has been shown to interact with PAK1,[3] PTK2,[4] PTPN21[5] and RUFY1.[6]

References

Further reading



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