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Ccl15

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Ccl15

chemokine (C-C motif) ligand 15
Identifiers
Symbol CCL15
Alt. symbols SCYA15, HCC-2, NCC-3, SCYL3, MIP-5, Lkn-1, MIP-1d, HMRP-2B
Entrez HUGO OMIM PDB 2HCC (RefSeq UniProt Locus q11.2

Chemokine (C-C motif) ligand 15 (CCL15) is a small cytokine belonging to the CC chemokine family that is also known as leukotactin-1, MIP5 and HCC-2. CCL15 is expressed in liver, small intestine, colon, and in certain leukocytes and macrophages of the lung.[1] It is chemotactic for neutrophils, monocytes, and lymphocytes and elicits its effects by binding to cell surface chemokine receptors like CCR1 and CCR3.[2][3] The human CCL15 gene spans four exons and is located in a head-to-tail orientation on chromosome 17 with the gene of another CC chemokine known as CCL14.[4]

References

External links

  • CCL15 GeneCard


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