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Extraglomerular mesangial cell

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Title: Extraglomerular mesangial cell  
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Language: English
Subject: Intraglomerular mesangial cell, Nephron, Lipoblast, Juxtaglomerular cell, External sphincter muscle of female urethra
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Extraglomerular mesangial cell

Diagram of renal corpuscle structure. Extraglomerular mesangial cell is #5b. A – Renal corpuscle B – Proximal tubule C – Distal convoluted tubule D – Juxtaglomerular apparatus 1. Basement membrane (Basal lamina) 2. Bowman's capsule – parietal layer 3. Bowman's capsule – visceral layer 3a. Pedicels (Foot processes from podocytes) 3b. Podocyte 4. Bowman's space (urinary space) 5a. Mesangium – Intraglomerular cell 5b. Mesangium – Extraglomerular cell 6. Granular cells (Juxtaglomerular cells) 7. Macula densa 8. Myocytes (smooth muscle) 9. Afferent arteriole 10. Glomerulus Capillaries 11. Efferent arteriole

Extraglomerular mesangial cells (also known as Lacis cells, Goormaghtigh cells, or Polkissen cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.

Lacis cells form the juxtaglomerular apparatus in combination with two other types of cells: the macula densa of the distal convoluted tubule and juxtaglomerular cells of the afferent arteriole. This apparatus controls blood pressure through the Renin-Angiotensin-Aldosterone system. The specific function of Lacis cells is not well understood, although it has been associated with the secretion of erythropoietin.[1]

See also

References

  1. ^ Junqueira, Luiz C.; Jose Carneiro (2003). Basic Histology. McGraw-Hill.  

External links

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