World Library  
Flag as Inappropriate
Email this Article

Flt1

Article Id: WHEBN0014075504
Reproduction Date:

Title: Flt1  
Author: World Heritage Encyclopedia
Language: English
Subject: Tyrosine kinase, FLT, Soluble fms-like tyrosine kinase-1, Chromosome 13 (human), Immunoglobulin domain, VEGF receptors
Collection:
Publisher: World Heritage Encyclopedia
Publication
Date:
 

Flt1

Fms-related tyrosine kinase 1
PDB rendering based on 1flt.
Available structures
PDB Ortholog search: RCSB
Identifiers
2.7.10.1
RNA expression pattern

Vascular endothelial growth factor receptor 1 is a protein that in humans is encoded by the FLT1 gene.[1]

Oncogene FLT belongs to the src gene family and is related to oncogene ROS (MIM 165020). Like other members of this family, it shows tyrosine protein kinase activity that is important for the control of cell proliferation and differentiation. The sequence structure of the FLT gene resembles that of the FMS gene (MIM 164770); hence, Yoshida et al. (1987) proposed the name FLT as an acronym for FMS-like tyrosine kinase.[supplied by OMIM][2]

Interactions

FLT1 has been shown to interact with PLCG1[3] and Vascular endothelial growth factor B.[4][5]

See also

References

Further reading


This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and USA.gov, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for USA.gov and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
 
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
 
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.
 


Copyright © World Library Foundation. All rights reserved. eBooks from Project Gutenberg are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.