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Heptabarb

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Title: Heptabarb  
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Subject: Alcoholic beverage, Spirobarbital, Centalun, Nitromethaqualone, Pentabamate
Collection: Barbiturates, Cycloalkenes, Gabaa Receptor Positive Allosteric Modulators, Hypnotics, Ketones, Pyrimidines, Sedatives
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Heptabarb

Heptabarb
Systematic (IUPAC) name
5-cyclohept-1-en-1-yl-5-ethylpyrimidine-2,4,6(1H,3H,5H)-trione
Clinical data
Pregnancy cat.
  • ?
Legal status
  • ?
Routes Oral[1]
Pharmacokinetic data
Bioavailability 83%[1]
Metabolism Hepatic
Half-life 6.1-11.2 hours[1]
Excretion Renal[1]
Identifiers
CAS number
ATC code N05
PubChem
DrugBank
ChemSpider  YesY
UNII  YesY
KEGG  YesY
ChEMBL  YesY
Synonyms G-475
Chemical data
Formula C13H18N2O3 
Mol. mass 250.294 g/mol
 YesY   

Heptabarb (INN; Eudan, Medapan, Medomin, Noctyn), also known as heptabarbitone (BAN) or heptabarbital, is a sedative and hypnotic drug of the barbiturate family.[2][3] It was previously used in Europe for the treatment of insomnia from the 1950s onwards, but has since been discontinued.[2][3]

See also

References

  1. ^ a b c d Breimer DD, de Boer AG (December 1975). "Pharmacokinetics and relative bioavailability of heptabarbital and heptabarbital sodium after oral administration to man". European Journal of Clinical Pharmacology 9 (2-3): 169–78.  
  2. ^ a b C. R Ganellin; D. J Triggle; F.. Macdonald (1997). Dictionary of pharmacological agents. CRC Press. p. 1003.  
  3. ^ a b Index nominum 2000: international drug directory. Taylor & Francis US. 2000. p. 513.  



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