Mirfentanil

Mirfentanil
Identifiers
CAS number 117523-47-4 YesY
PubChem 60698
Jmol-3D images {{#if:C1CN(CCC1N(C2=NC=CN=C2)C(=O)

C3=CC=CO3)CCC4=CC=CC=C4|Image 1

Properties
Molecular formula C22H24N4O2
Molar mass 376.45 g mol−1
 YesY (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Mirfentanil is a fentanyl derivative with strong selectivity for the μ opioid receptor. At lower doses, it antagonizes the analgesic effects of alfentanil and substitutes for naloxone in morphine-treated monkeys; however, it also reverses naloxone-precipitated withdrawal in pigeons trained to discriminate morphine from naloxone.[1]

At high doses, it exhibits analgesic activity which is not fully reversed by opioid antagonists, suggesting that the drug has both opioid and non-opioid mechanisms of action.[1][2]

References

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