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Title: Naloxonazine  
Author: World Heritage Encyclopedia
Language: English
Subject: Naloxazone, List of opioids, Hydrocodone, Tetrahydrocannabinol, Kobret
Collection: Alkenes, Alkylating Agents, Irreversible Receptor Antagonists, Morphinans, Opioid Antagonists, Phenols, Semisynthetic Opioids
Publisher: World Heritage Encyclopedia


CAS number  YesY
ChemSpider  N
IUPHAR ligand
Jmol-3D images Image 1
Molecular formula C38H42N4O6
Molar mass 650.76 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N   YesY/N?)

Naloxonazine is a potent irreversible mu opioid antagonist.[1] Naloxonazine forms spontaneously in acidic solutions of naloxazone, and may be responsible for much or all of the irreversible μ opioid receptor binding displayed by the latter.[2]

See also


  1. ^ Naloxonazine dihydrochloride
  2. ^ Hahn, E. F.; Pasternak, G. W. (September 1982). "Naloxonazine, a potent, long-lasting inhibitor of opiate binding sites".  
  3. ^ Image of OM-3-MNZ

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