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P2ry14

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P2ry14

Purinergic receptor P2Y, G-protein coupled, 14
Available structures
PDB Ortholog search: RCSB
Identifiers
P2RY14 Gene
RNA expression pattern

P2Y purinoceptor 14 is a protein that in humans is encoded by the P2RY14 gene.[1]

The product of this gene, P2Y14 belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene.[1]

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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