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Pentolinium

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Title: Pentolinium  
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Subject: Ganglionic blocker, Nicotinic antagonist, Guanazodine, Guanoxan, Guanochlor
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Pentolinium

Pentolinium
Systematic (IUPAC) name
1-methyl-1-[5-(1-methylpyrrolidin-1-ium-1-yl)pentyl]pyrrolidin-1-ium
Identifiers
CAS Registry Number
52-62-0 (tartrate salt)
PubChem CID:
DrugBank
ChemSpider
UNII
ChEMBL
Chemical data
Formula C15H32N2
Molecular mass 240.43 g/mol

Pentolinium is a ganglionic blocking agent which acts as a nicotinic acetylcholine receptor antagonist. It can be used as an antihypertensive drug during surgery or to control hypertensive crises. It works by binding to the acetylcholine receptor of adrenergic nerves and thereby inhibiting the release of noradrenaline and adrenaline. Blocking this receptor leads to smooth muscle relaxation and vasodilatation. Pentolinium can be given orally, injected intramuscularly or administered intravenously.

Overview

It's molecular formula is C15H32N2+2.[1]

References

  1. ^ http://pubchem.ncbi.nlm.nih.gov/compound/Pentolinium#section=Top

External links

  • DrugBank: Pentolinium



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