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Title: Propacetamol  
Author: World Heritage Encyclopedia
Language: English
Subject: Analgesic, Cyclorphan, Glafenine, Proxorphan, Psychotridine
Publisher: World Heritage Encyclopedia


Systematic (IUPAC) name
4-(acetamido)phenyl N,N-diethylglycinate
Clinical data
Routes of
Pharmacokinetic data
Biological half-life 2.4 hours [1]
Excretion Renal
CAS Registry Number
ATC code N02
PubChem CID:
Chemical data
Formula C14H20N2O3
Molecular mass 264.3202 g/mol

Propacetamol is a prodrug form of paracetamol which is formed from esterification of paracetamol, and the carboxylic acid diethylglycine. This has the advantage of making it more water-soluble. It is used in post-operative care and is delivered by I.V.[2] It is given if the patient is unable to take oral or rectally delivered paracetamol and non-steroidal anti-inflammatory drugs are contraindicated. The onset of analgaesia from propacetamol is more rapid than paracetamol given orally.[3] 2 g of propacetamol are equivalent to 1g of paracetamol.[4]

See also


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