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Renal chloride reabsorption

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Renal chloride reabsorption

Renal reabsorption of chloride (Cl) is a part of renal physiology, in order not to lose too much chloride in the urine.

Overview table

Characteristics of Cl reabsorption
Characteristic proximal tubule loop of Henle Distal convoluted tubule Collecting duct system
S1 S2 S3 descending limb thin ascending limb thick ascending limb connecting tubule initial collecting tubule cortical collecting ducts medullary collecting ducts
reabsorption (%)
reabsorption (mmoles/day)
Concentration (mM) 115[1] 135[1]
electrical driving force (mV) −3[2] +3[2] +15[2] −5 to +5[2] −40[2]
chemical driving force (mV)
electrochemical driving force (mV) (positive) [3]
apical transport proteins (passively)[3]
basolateral transport proteins chloride channels

β intercalated cells: ClHCO3 exchanger[1]

Other reabsorption features

References

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