World Library  
Flag as Inappropriate
Email this Article


Article Id: WHEBN0022298512
Reproduction Date:

Title: 1,3-Diaminopropane  
Author: World Heritage Encyclopedia
Language: English
Subject: Glycine, MMPIP, LY-344,545, PEAQX, Tetrazolylglycine
Publisher: World Heritage Encyclopedia


Skeletal formula of 1,3-diaminopropane
Abbreviations TMEDA
CAS number  YesY
ChemSpider  YesY
EC number
UN number 2922
RTECS number TX6825000
Beilstein Reference 605277
Gmelin Reference 1298
Jmol-3D images Image 1
Molecular formula C3H10N2
Molar mass 74.12 g mol−1
Appearance Colourless liquid
Odor Fishy, ammoniacal
Density 888 mg mL−1
Melting point −12.00 °C; 10.40 °F; 261.15 K
Boiling point 140.1 °C; 284.1 °F; 413.2 K
log P −1.4
Vapor pressure <1.1 kPa or 11.5 mm Hg(at 20 °C)
Refractive index (nD) 1.458
GHS pictograms The flame pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) The corrosion pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS) The skull-and-crossbones pictogram in the Globally Harmonized System of Classification and Labelling of Chemicals (GHS)
GHS signal word DANGER
GHS hazard statements H226, H302, H310, H314
GHS precautionary statements P280, P302+350, P305+351+338, P310
EU classification Toxic T Corrosive C
R-phrases R10, R22, R24, R35
S-phrases S26, S36/37/39, S45
Flash point 51 °C (124 °F; 324 K)
Autoignition temperature 350 °C (662 °F; 623 K)
Explosive limits 2.8–15.2%
  • 177 mg kg−1 (dermal, rabbit)
  • 700 mg kg−1 (oral, rat)
Related compounds
Related alkanamines
Related compounds 2-Methyl-2-nitrosopropane
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 YesY   YesY/N?)

1,3-Diaminopropane, also known as trimethylenediamine, is a simple 1,2-diaminopropane. Both are building blocks in the synthesis of heterocycles, such as those used in textile finishing, and coordination complexes. It is prepared by the amination of acrylonitrile followed by hydrogenation of the resulting aminopropionitrile.[1]

The potassium salt was used in the alkyne zipper reaction.[2]


Diamines are typically skin irritants.


  1. ^ Karsten Eller, Erhard Henkes, Roland Rossbacher, Hartmut Höke "Amines, Aliphatic" in Ullmann's Encyclopedia of Industrial Chemistry, Wiley-VCH, Weinheim, 2005. doi:10.1002/14356007.a02_001
  2. ^ C. A. Brown and A. Yamashita (1975). "Saline hydrides 2and superbases in organic reactions. IX. Acetylene zipper. Exceptionally facile contrathermodynamic multipositional isomeriazation of alkynes with potassium 3-aminopropylamide".  
This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.

Copyright © World Library Foundation. All rights reserved. eBooks from Project Gutenberg are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.