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Title: 2-Oleoylglycerol  
Author: World Heritage Encyclopedia
Language: English
Subject: Stearoylethanolamide, Docosatetraenoylethanolamide, Arachidonoyl serotonin, Oleoylethanolamide, N-Arachidonoyl dopamine
Publisher: World Heritage Encyclopedia


IUPAC name
1,3-dihydroxypropan-2-yl (Z)-octadec-9-enoate
Other names
identifiersIdentifiers[http:// http://]
ChemSpider  YesY
Jmol-3D images Image
Molar mass 356.55 g·mol−1
Density 0.958 g/cm3
Flash point >113.0 °C
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
 YesY  (: YesY/N?)

2-Oleoylglycerol (2OG) is a monoacylglycerol that is found in biologic tissues. Its synthesis is derived from diacylglycerol precursors. It is metabolized to oleic acid and glycerol primarily by the enzyme monoacylglycerol lipase (MAGL).[1] In 2011, 2OG was found to be an endogenous ligand to GPR119.[2] 2OG has been shown to increase glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP) levels following administration to the small intestine.[2]

See also


  1. ^
  2. ^ a b

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