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4-Phenyl-4-(1-piperidinyl)cyclohexanol

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Title: 4-Phenyl-4-(1-piperidinyl)cyclohexanol  
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4-Phenyl-4-(1-piperidinyl)cyclohexanol

4-Phenyl-4-(1-piperidinyl)cyclohexanol
Identifiers
CAS number
PubChem
ChemSpider  YesY
Jmol-3D images Image 1
Image 2
Properties
Molecular formula C17H25NO
Molar mass 259.391 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 YesY   YesY/N?)

4-Phenyl-4-(1-piperidinyl)-cyclohexanol, also known as PPC, is an metabolite of phencyclidine (PCP).[1] It can be detected in the hair of PCP users.[2]

PPC has been shown to cause increases in locomotor activity in lab mice.[3]

See also

  • PCHP, another PCP metabolite

References

  1. ^ Nabeshima, Toshitaka; Yamaguchi, Kazumasa; Fukaya, Hiroaki; Hiramatsu, Masayuki; Furukawa, Hiroshi; Kameyama, Tsutomu (1985). "Simultaneous determination of phencyclidine and its major metabolites in biological samples by high-performance liquid chromatography". Research Communications in Substances of Abuse 6 (2): 65–78. 
  2. ^ Nakahara, Yuji; Takahashi, Kazunori; Sakamoto, Tomoaki; Tanaka, Akira; Hill, Virginia A.; Baumgartner, Werner A. (1997). "Hair analysis for drugs of abuse XVII. Simultaneous detection of PCP, PCHP, and PCPdiol in human hair for confirmation of PCP use". Journal of Analytical Toxicology 21 (5): 356–362.  
  3. ^ "Behavioral effects of phencyclidine and its major metabolite, (trans)4-phenyl-4-(1-piperidinyl)cyclohexanol, in mice". 
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