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Alprenolol

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Title: Alprenolol  
Author: World Heritage Encyclopedia
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Subject: Beta blockers, Iodocyanopindolol, Cyanopindolol, Tertatolol, Revospirone
Collection: Alcohols, Alkenes, Amines, Beta Blockers, Phenol Ethers
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Alprenolol

Alprenolol
Systematic (IUPAC) name
(RS)-1-(2-allylphenoxy)-3-(isopropylamino)propan-2-ol
Clinical data
AHFS/Drugs.com
Legal status
?
Routes Oral
Pharmacokinetic data
Protein binding 80% - 90%
Half-life 2-3 hours → 4-OH-alprenolol
Identifiers
CAS number  YesY
ATC code C07
PubChem
IUPHAR ligand
DrugBank
ChemSpider  YesY
UNII  YesY
KEGG  YesY
ChEBI  YesY
ChEMBL  YesY
Chemical data
Formula C15H23NO2 
Mol. mass 249.34 g/mol
 YesY   

Alprenolol, or alfeprol, alpheprol, and alprenololum (Gubernal, Regletin, Yobir, Apllobal, Aptine, Aptol Duriles), is a non-selective beta blocker as well as 5-HT1A receptor antagonist, used in the treatment of angina pectoris.[1] It is no longer marketed by AstraZeneca, but may still be available from other pharmaceutical companies or generically.

References

  1. ^ Hickie JB (August 1970). "Alprenolol ("aptin") in angina pectoris. A double-blind multicentre trial". Med. J. Aust. 2 (6): 268–72.  
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