World Library  
Flag as Inappropriate
Email this Article

Anileridine

Article Id: WHEBN0005127881
Reproduction Date:

Title: Anileridine  
Author: World Heritage Encyclopedia
Language: English
Subject: List of Fentanyl analogues, Acetylfentanyl, Phenoperidine, Pethidine, Fentanyl
Collection: Analgesics, Anilines, Ethyl Esters, General Anesthetics, Mu-Opioid Agonists, Piperidines, Synthetic Opioids
Publisher: World Heritage Encyclopedia
Publication
Date:
 

Anileridine

Anileridine
Systematic (IUPAC) name
Ethyl 1-[2-(4-aminophenyl)ethyl]-4-phenylpiperidine-4-carboxylate
Clinical data
AHFS/Drugs.com
Legal status
Routes of
administration
Tablets, injection
Pharmacokinetic data
Protein binding > 95%
Metabolism Hepatic
Identifiers
CAS Registry Number  Y
ATC code N01
PubChem CID:
IUPHAR/BPS
DrugBank  Y
ChemSpider  Y
UNII  Y
KEGG  Y
ChEBI  Y
ChEMBL  N
Chemical data
Formula C22H28N2O2
Molecular mass 352.47 g/mol
Physical data
Melting point 83 °C (181 °F)
 N   

Anileridine (trade name: Leritine) is a synthetic analgesic drug and is a member of the piperidine class of analgesic agents developed by Merck & Co. in the 1950s.[1] It differs from pethidine (meperidine) in that the N-methyl group of meperidine is replaced by an N-aminophenethyl group, which increases its analgesic activity.

Anileridine is no longer manufactured in the US or Canada.[2]

Administration

As tablets or injection.[3]

Pharmacokinetics

Anileridine usually takes effect within 15 minutes of either oral or intravenous administration, and lasts 2–3 hours.[4] It is mostly metabolized by the liver.

References

  1. ^ U.S. Patent 2,897,204
  2. ^ "Discontinued Prescription Drug Products". Canadian Pharmacists' Association. Retrieved 28 July 2008. 
  3. ^ "Pharmaceutical Information - LERITINE". RxMed. Retrieved 16 June 2010. 
  4. ^ "Anileridine Consumer Information". MedicineNet. Retrieved 28 July 2008. 



This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and USA.gov, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for USA.gov and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
 
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
 
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.
 


Copyright © World Library Foundation. All rights reserved. eBooks from Project Gutenberg are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.