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Arginylglycylaspartic acid

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Arginylglycylaspartic acid

Arginylglycylaspartic acid

Identifiers
Abbreviations RGD Peptide
CAS number 99896-85-2 YesY
PubChem 104802 YesY
ChemSpider 94603 YesY
MeSH arginyl-glycyl-aspartic+acid
Jmol-3D images Image 1
Properties
Molecular formula C12H22N6O6
Molar mass 346.34 g mol−1
log P −3.016
Acidity (pKa) 2.851
Basicity (pKb) 11.146
 N (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Arginylglycylaspartic acid (RGD) is a tripeptide composed of L-arginine, glycine, and L-aspartic acid. The sequence is a common element in cellular recognition.[1] Arginylglycylaspartic acid is used as a biochemical tool in the study of this recognition.

RGD-peptides are implicated in cellular attachment via integrins, and can be used to coat synthetic scaffolds in tissue engineering to enhance cellular attachment by mimicking in vivo conditions.[2]

References

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