World Library  
Flag as Inappropriate
Email this Article

Bactericide

Article Id: WHEBN0000004187
Reproduction Date:

Title: Bactericide  
Author: World Heritage Encyclopedia
Language: English
Subject: Pesticide, Pharmacology, Hygrophorus eburneus, Bacteria, Bactericides
Collection: Bactericides
Publisher: World Heritage Encyclopedia
Publication
Date:
 

Bactericide

A bactericide or bacteriocide, sometimes abbreviated Bcidal, is a substance that kills bacteria. Bactericides are disinfectants, antiseptics, or antibiotics.[1]

Contents

  • Bactericidal disinfectants 1
  • Bactericidal antiseptics 2
  • Bactericidal antibiotics 3
  • References 4
  • See also 5

Bactericidal disinfectants

The most used disinfectants are those applying

Bactericidal antiseptics

As antiseptics (i.e., germicide agents that can be used on human or animal body, skin, mucoses, wounds and the like), few of the above-mentioned disinfectants can be used, under proper conditions (mainly concentration, pH, temperature and toxicity toward humans and animals). Among them, some important are

Others are generally not applicable as safe antiseptics, either because of their corrosive or toxic nature.

Bactericidal antibiotics

Bactericidal antibiotics kill bacteria; bacteriostatic antibiotics slow their growth or reproduction.

Antibiotics that inhibit cell wall synthesis: the Beta-lactam antibiotics (penicillin derivatives (penams), cephalosporins (cephems), monobactams, and carbapenems) and vancomycin.

Also bactericidal are daptomycin, fluoroquinolones, metronidazole, nitrofurantoin, co-trimoxazole, telithromycin.

Aminoglycosidic antibiotics are usually considered bactericidal, although they may be bacteriostatic with some organisms

The distinction between bactericidal and bacteriostatic agents appears to be clear according to the basic/clinical definition, but this only applies under strict laboratory conditions and it is important to distinguish microbiological and clinical definitions. The distinction is more arbitrary when agents are categorized in clinical situations. The supposed superiority of bactericidal agents over bacteriostatic agents is of little relevance when treating the vast majority of infections with gram-positive bacteria, particularly in patients with uncomplicated infections and noncompromised immune systems. Bacteriostatic agents have been effectively used for treatment that are considered to require bactericidal activity. Furthermore some broad classes of antibacterial agents considered bacteriostatic can exhibit bactericidal activity against some bacteria on the basis of in vitro determination of MBC/MIC values. At high concentrations, bacteriostatic agents are often bactericidal against some susceptible organisms The ultimate guide to treatment of any infection must be clinical outcome.[2]

References

  1. ^ Klaus Grünewald: Theorie der medizinischen Fußbehandlung 1: Ein Fachbuch für Podologie. 3. Auflage. Verlag Neuer Merkur GmbH, 2006, ISBN 3-929360-60-8, S. 232 (Digitalitat)
  2. ^ http://cid.oxfordjournals.org/content/38/6/864.long

See also

This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and USA.gov, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for USA.gov and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
 
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
 
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.
 


Copyright © World Library Foundation. All rights reserved. eBooks from Project Gutenberg are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.