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Ccl13

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Subject: Chemokine, Chromosome 17 (human), CC chemokine receptors
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Ccl13

chemokine (C-C motif) ligand 13
Identifiers
Symbol CCL13
Alt. symbols SCYA13, MCP-4, NCC-1, SCYL1, CKb10
Entrez HUGO OMIM RefSeq UniProt Locus q11.2

Chemokine (C-C motif) ligand 13 (CCL13) is a small cytokine belonging to the CC chemokine family. Its gene is located on human chromosome 17 within a large cluster of other CC chemokines.[1][2] CCL13 induces chemotaxis in monocytes, eosinophils, T lymphocytes, and basophils by binding cell surface G-protein linked chemokine receptors such as CCR2, CCR3 and CCR5.[3] Activity of this chemokine has been implicated in allergic reactions such as asthma.[4] CCL13 can be induced by the inflammatory cytokines interleukin-1 and TNF-α.

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