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Ccl27

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Subject: Chemokine, Chromosome 9 (human), CC chemokine receptors
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Ccl27

chemokine (C-C motif) ligand 27
Identifiers
Symbol CCL27
Alt. symbols SCYA27, ALP, ILC, CTACK, skinkine, ESkine, PESKY, CTAK
Entrez HUGO OMIM RefSeq UniProt Locus q13

Chemokine (C-C motif) ligand 27 (CCL27) is a small cytokine belonging to the CC chemokine family also known under the names IL-11 R-alpha-locus chemokine (ILC), Skinkine, ESkine and Cutaneous T-cell-attracting chemokine (CTACK). It is associated with homing of memory T lymphocytes to the skin, and plays a role in T cell-mediated inflammation of the skin.[1][2] CCL27 is expressed in numerous tissues, including gonads, thymus, placenta and skin. It elicits its chemotactic effects by binding to the chemokine receptor CCR10.[3] The gene for CCL27 is located on human chromosome 9.[4]

References


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