World Library  
Flag as Inappropriate
Email this Article

Dimethylamphetamine

Article Id: WHEBN0014583981
Reproduction Date:

Title: Dimethylamphetamine  
Author: World Heritage Encyclopedia
Language: English
Subject: Etilamfetamine, Fencamine, 3,4-Dimethylmethcathinone, 3-Fluoromethcathinone, 3-Fluoroethamphetamine
Collection:
Publisher: World Heritage Encyclopedia
Publication
Date:
 

Dimethylamphetamine

Dimethylamphetamine
Systematic (IUPAC) name
N,N-dimethyl-1-phenylpropan-2-amine
Clinical data
Legal status
Routes Oral
Identifiers
CAS number  YesY
ATC code None
PubChem
ChemSpider  YesY
Chemical data
Formula C11H17N 
Mol. mass 163.259 g/mol
 YesY   

Dimethylamphetamine (Metrotonin), also known as dimetamfetamine (INN) and N,N-dimethylamphetamine, is a stimulant drug of the phenethylamine and amphetamine chemical classes. Dimethylamphetamine has weaker stimulant effects than amphetamine or methamphetamine and is considerably less addictive[1] and less neurotoxic compared to methamphetamine.[2][3] However, it still retains some mild stimulant effects and abuse potential,[4] and is a Schedule I controlled drug.

Dimethylamphetamine has occasionally been found in illicit methamphetamine laboratories, but is usually an impurity rather than the desired product. It may be produced by accident when methamphetamine is synthesised by methylation of amphetamine if the reaction temperature is too high or an excess of methylating agent is used.[5][6]

References

  1. ^ Witkin JM, Ricaurte GA, Katz JL. Behavioral effects of N-methylamphetamine and N,N-dimethylamphetamine in rats and squirrel monkeys. Journal of Pharmacology and Experimental Therapeutics. 1990 May;253(2):466-74.
  2. ^ Ricaurte GA, DeLanney LE, Irwin I, Witkin JM, Katz JL, Langston JW. Evaluation of the neurotoxic potential of N,N-dimethylamphetamine: an illicit analog of methamphetamine. Brain Research. 1989 Jun 26;490(2):301-6.
  3. ^ Fasciano J, Hatzidimitriou G, Yuan J, Katz JL, Ricaurte GA. N-methylation dissociates methamphetamine's neurotoxic and behavioral pharmacologic effects. Brain Research. 1997 Oct 10;771(1):115-20.
  4. ^ Katz JL, Ricaurte GA, Witkin JM. Reinforcing effects of enantiomers of N,N-dimethylamphetamine in squirrel monkeys. Psychopharmacology (Berlin). 1992;107(2-3):315-8.
  5. ^ US Drug Enforcement Administration: Microgram Bulletin
  6. ^ US Drug Enforcement Administration: The Identification of d-N,N-Dimethylamphetamine (DMA) in an Exhibit in Malaysia



This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and USA.gov, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for USA.gov and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
 
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
 
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.
 


Copyright © World Library Foundation. All rights reserved. eBooks from Project Gutenberg are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.