World Library  
Flag as Inappropriate
Email this Article

Eptazocine

Article Id: WHEBN0033911992
Reproduction Date:

Title: Eptazocine  
Author: World Heritage Encyclopedia
Language: English
Subject: List of opioids, Kobret, 6β-Naltrexol-d4, Hemorphin, Naloxonazine
Collection: Alcohols, Analgesics, Opioids
Publisher: World Heritage Encyclopedia
Publication
Date:
 

Eptazocine

Eptazocine
Systematic (IUPAC) name
(1S,6S)-1,4-dimethyl-2,3,4,5,6,7-hexahydro-1H-1,6-methano-4-benzazonin-10-ol
Clinical data
Legal status
  • Prescription only
Routes Oral
Identifiers
CAS number
72150-17-5 (bromide)
ATC code None
PubChem
ChemSpider
UNII
Chemical data
Formula C15H21NO 
Mol. mass 231.333 g/mol

Eptazocine (Sedapain) is an opioid analgesic which was introduced in Japan by Morishita in 1987.[1][2][3][4] It acts as a mixed κ-opioid receptor agonist and μ-opioid receptor antagonist.[4][5][6]

See also

References

  1. ^ Index nominum 2000: international drug directory. Taylor & Francis US. 2000. p. 396.  
  2. ^ American Chemical Society. Division of Medicinal Chemistry (1990). Annual Reports in Medicinal Chemistry. Academic Press. p. 381.  
  3. ^ Nabeshima T, Matsuno K, Kamei H, Kameyama T (May 1985). "The interaction of eptazocine, a novel analgesic, with opioid receptors". Research Communications in Chemical Pathology and Pharmacology 48 (2): 173–81.  
  4. ^ a b Hiroshi Nagase; Silvia N. Calderon (21 January 2011). Chemistry of Opioids. Springer. p. 280.  
  5. ^ Tamura T, Ogawa J, Taniguchi T, Waki I (January 1990). "[Preferential action of eptazocine, a novel analgesic, with opioid receptors in isolated guinea pig ileum and mouse vas deferens preparations]". Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica (in Japanese) 95 (1): 41–6.  
  6. ^ Dr. Ian Morton; Ian K. M. Morton; Judith M. Hall; Dr. Judith Hall (1999). Concise dictionary of pharmacological agents: properties and synonyms. Springer. p. 113.  


This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and USA.gov, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for USA.gov and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
 
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
 
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.
 


Copyright © World Library Foundation. All rights reserved. eBooks from Project Gutenberg are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.