World Library  
Flag as Inappropriate
Email this Article

Fournier gangrene

Article Id: WHEBN0008187420
Reproduction Date:

Title: Fournier gangrene  
Author: World Heritage Encyclopedia
Language: English
Subject: Penectomy, 311, Galerius, List of diseases (F), Gangrene, Necrotizing fasciitis, List of eponymously named diseases, Ramón Emeterio Betances, Tim Maia, Ioannis Kyrastas
Publisher: World Heritage Encyclopedia

Fournier gangrene

Fournier gangrene
Classification and external resources
10 9 DiseasesDB eMedicine MeSH D018934

Fournier gangrene is a type of necrotizing infection or gangrene usually affecting the perineum.

It was first described by Baurienne in 1764 and is named after a French venereologist, Jean Alfred Fournier following five cases he presented in clinical lectures in 1883.


In the majority of cases Fournier gangrene is a mixed infection caused by both aerobic and anaerobic bacteria.[1] Death can result from Fournier gangrene.[2]


An estimated 750 cases have been reported in the literature,[3] with most patients in their 60s or 70s with other concurrent illnesses.[4] According to another study in 2000, there have been at least 1726 reported cases in the English literature.[5] However, Fournier gangrene is not a reportable illness, so the number of unreported cases is unclear. A similar infection in women has been occasionally described.[6]

In Turkey it was reported that 46% of patients had diabetes mellitus[7] while other studies have identified approximately a third of patients having either diabetes, alcoholism or malnutrition, and 10% having medical immunosuppression (chemotherapy, steroids, or malignancy).[8]


Fournier gangrene is an urological emergency requiring intravenous antibiotics and debridement (surgical removal) of necrotic (dead) tissue. In addition to surgery and antibiotics, hyperbaric oxygen therapy (HBOT) may be useful and acts to inhibit the growth of and kill the anaerobic bacteria.[9] Despite such measures, the mortality rate overall is 40%, but 78% if sepsis is already present at the time of initial hospital admission.[7]

Notable Cases

The most historically prominent sufferers from this condition may have been Herod the Great, his grandson Herod Agrippa, and possibly the Roman emperor Galerius. Puerto Rican abolitionist and pro-independence leader Segundo Ruiz Belvis died from Fournier gangrene in November 1867.[10]

See also


External links

  • Jean Alfred Fournier at Who Named It?
This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.

Copyright © World Library Foundation. All rights reserved. eBooks from Project Gutenberg are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.