World Library  
Flag as Inappropriate
Email this Article

Fumonisin

Article Id: WHEBN0005499963
Reproduction Date:

Title: Fumonisin  
Author: World Heritage Encyclopedia
Language: English
Subject: Molecularly imprinted polymer, Mycotoxins, Chinese pickles, Beta-Bungarotoxin, Cardiotoxin III
Collection: Mycotoxins
Publisher: World Heritage Encyclopedia
Publication
Date:
 

Fumonisin

A fumonisin is a mycotoxin derived from Fusarium, Liseola section.[1] They have strong structural similarity to sphinganine, the backbone precursor of sphingolipids[2]

More specifically, it can refer to:

The trichothecene (T-2) mycotoxins are a group of over 40 compounds produced by fungi of the genus Fusarium, a common grain mold.[3]

The estrogenic metabolite, zearalenone, is also referred to as F-2 toxin.[4]

As the fumonisins appear to be non-genotoxic the possibility that they belong to another class of non-genotoxic carcinogens, the peroxisome proliferators, was investigated[5]

Genetic engineering is reported as a promising means of detoxifying mycotoxins. This approach may provide innovative solutions to the problem of fumonisin in corn.[6]

At least 15 different fumonisins have so far been reported and other minor metabolites have been identified, although most of them have not been shown to occur naturally.[7] In 2015, a unique class of non-aminated fumonisins[8] was reported on grapes infected with Aspergillus welwitschia, although their toxicities have not yet been established.

References

  1. ^ Fumonisins at the US National Library of Medicine Medical Subject Headings (MeSH)
  2. ^ Gelderblom, Wentzel C. A.; Marasas, Walter F. O.; Vleggaar, R.; Thiel, Pieter G.; Cawood, M. E. (February 1992). "Fumonisins: Isolation, chemical characterization and biological effects". Mycopathologia 117 (1-2): 11–16.  
  3. ^ USAMRIID's Medical Management of Biological Casualties Handbook, 6th Ed. McLean, VA: International Medical Publishing, Inc. 2005. pp. 102–103.  
  4. ^ Marasas, W.F.O.; Paul E. Nelson (1987). Mycotoxicology: Introduction to the Mycology, Plant Pathology, Chemistry, Toxicology, and Pathology of Naturally Occurring Mycotoxicoses In Animals and Man. University Park, PA: The Pennsylvania State University Press. p. 47.  
  5. ^ Jackson, Lauren S.; Jonathan W. DeVries; Lloyd B. Bullerman (1996). Fumonisins In Food. New York, NY: Plenum Press. p. 289.  
  6. ^ "Reduced contamination by the Fusarium mycotoxin zearalenone in maize kernels through genetic modification with a detoxification gene.". Appl Environ Microbiol 73 (5): 1622–9. March 2007.  
  7. ^ Marasas, W.F.O.; J.D. Miller; R.T. Riley; A. Visconti (2000). Environmental Health Criteria 219: Fumonisin B1. Vammala, Finland: World Health Organization. p. 9.  
  8. ^ Renaud, J.B.R; M.J Kelman; Tianyu F. Qi; K.A. Seifert; M.W. Sumarah (2015). Product ion filtering with rapid polarity switching for the detection of all fumonisins and AAL-toxins. Rapid Communications in Mass Spectrometry Volume 29, Issue 22, 30 November 2015, Pages 2131–2139. 


This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and USA.gov, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for USA.gov and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
 
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
 
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.
 


Copyright © World Library Foundation. All rights reserved. eBooks from Project Gutenberg are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.