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Ifnar1

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Title: Ifnar1  
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Subject: Interferon, Peginterferon alfa-2b, Interferon type I, Interferon-alpha/beta receptor, Tyrosine kinase 2, STAT2
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Ifnar1

Interferon (alpha, beta and omega) receptor 1
Available structures
PDB Ortholog search: RCSB
Identifiers
IFNAR1 Gene
RNA expression pattern

Interferon-alpha/beta receptor alpha chain is a protein that in humans is encoded by the IFNAR1 gene.[1][2]

The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.[2]

Interactions

IFNAR1 has been shown to interact with STAT2,[3][4][5] Tyrosine kinase 2[6][7] and PRMT1.[8]

References

Further reading



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