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Kcnj8

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Kcnj8

Potassium inwardly-rectifying channel, subfamily J, member 8
Identifiers
KCNJ8 Gene
RNA expression pattern

Potassium inwardly-rectifying channel, subfamily J, member 8, also known as KCNJ8, is a human gene encoding the Kir6.1 protein.[1] A mutation in KCNJ8 has been associated with cardiac arrest in the early repolarization syndrome.

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. Kir6.1 is an integral membrane protein and inward-rectifier type potassium channel. Kir6.1, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins.[1]

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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