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Lilra2

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Title: Lilra2  
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Subject: Leukocyte immunoglobulin-like receptors, CD3 (immunology), CD79B, IL18R1, CD16
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Lilra2

Leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols  ; CD85H; ILT1; LIR-7; LIR7
External IDs GeneCards:
RNA expression pattern
Orthologs
Species Human Mouse
Entrez n/a
Ensembl n/a
UniProt n/a
RefSeq (mRNA) n/a
RefSeq (protein) n/a
Location (UCSC) n/a
PubMed search n/a

Leukocyte immunoglobulin-like receptor subfamily A member 2 is a protein that in humans is encoded by the LILRA2 gene.[1][2][3] Leukocyte Ig-like receptors (LIRs) are a family of immunoreceptors expressed predominantly on monocytes and B cells and at lower levels on dendritic cells and natural killer (NK) cells. All LIRs in subfamily B have an inhibitory function (see, e.g., LILRB1, MIM 604811). LIRs in subfamily A, with short cytoplasmic domains lacking an immunoreceptor tyrosine-based inhibitory motif (ITIM) and with transmembrane regions containing a charged arginine residue, may initiate stimulatory cascades. One member of subfamily A (LILRA3; MIM 604818) lacks a transmembrane region and is presumed to be a soluble receptor.[supplied by OMIM][3]

See also

References

  1. ^
  2. ^
  3. ^ a b

Further reading

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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