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Nacolomab tafenatox

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Title: Nacolomab tafenatox  
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Subject: List of drugs: N-Na, Detumomab, Minretumomab, Sibrotuzumab, Indium (111In) igovomab
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Nacolomab tafenatox

Nacolomab tafenatox?
Monoclonal antibody
Type Fab fragment
Source Mouse
Target colorectal tumor antigen C242
Identifiers
CAS Registry Number  N
ATC code None
 N   

Nacolomab tafenatox is a mouse monoclonal antibody[1] designed for the treatment of colorectal cancer. The antibody itself, nacolomab, is fused with enterotoxin A from Staphylococcus aureus (which is reflected by 'tafenatox' in the drug's name).[1]

Schematic image of nacolomab tafenatox.
VH, VL: variable (antigen binding) domains of antibody fragment
CH1, CL: constant domains of antibody fragment
SAg: enterotoxin A (acting as a superantigen)

See also

References

  1. ^ a b WHO Drug Information


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