Pentamorphone

Pentamorphone (14β-pentylaminomorphinone, RX-77989) is a semi-synthetic opiate derivative related to compounds such as morphine, hydromorphone and oxymorphone. Developed in 1984, it is a potent opioid analgesic several times stronger than fentanyl, and with a similarly fast onset of effects and short duration of action.[1][2] It was found to produce relatively little respiratory depression compared to other potent opioid agonists,[3] but its analgesic effects were somewhat disappointing in human trials,[4] and while pentamorphone had some slight advantages over fentanyl[5] these were not sufficient to warrant its introduction into clinical use.

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