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Ru-58841

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Title: Ru-58841  
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Subject: Antiandrogens, Methandriol, Cyanoketone, 11-Ketotestosterone, AC-262,356
Collection: Antiandrogens, Hydantoins
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Ru-58841

RU-58841
Systematic (IUPAC) name
4-[3-(4-Hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl]-2-(trifluoromethyl)benzonitrile
Identifiers
CAS Registry Number
PubChem CID:
Chemical data
Formula C17H18F3N3O3
Molecular mass 369.3 g/mol

RU-58841 is an experimental drug candidate which is intended for use as a topical treatment for acne, androgenetic alopecia, and hirsutism.[1][2] The compound is similar in structure to RU-58642 but contains a different side-chain.[3] These compounds are non-steroidal anti-androgen drugs similar to nilutamide,[4] which is related to flutamide, bicalutamide, and enzalutamide. RU58841 can be synthesized either by building the hydantoin moiety or by aryl coupling to 5,5-dimethylhydantoin [5]

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