World Library  
Flag as Inappropriate
Email this Article

Rate of infusion

Article Id: WHEBN0018872320
Reproduction Date:

Title: Rate of infusion  
Author: World Heritage Encyclopedia
Language: English
Subject: Pharmacology, Antimicrobial pharmacodynamics, Effective dose (pharmacology), Reverse pharmacology, Superagonist
Publisher: World Heritage Encyclopedia

Rate of infusion

In pharmacokinetics, the rate of infusion (or dosing rate) refers not just to the rate at which a drug is administered, but the desired rate at which a drug should be administered to achieve a steady state of a fixed dose which has been demonstrated to be therapeutically effective.

Abbreviations include Kin, [1] K0, [2] or R0.

It can be calculated as the steady-state concentration in the plasma multiplied by the clearance:

\textstyle K_{in} = C_{ss} \cdot CL


  1. ^ "Cp vs time - iv infusion". 
  2. ^ "Chapter 15.2 - Continuous IV Infusion - Steady State". 
This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.

Copyright © World Library Foundation. All rights reserved. eBooks from Project Gutenberg are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.