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Title: Serlopitant  
Author: World Heritage Encyclopedia
Language: English
Subject: List of drugs: Se-Sh, SNAP-94847, Meclinertant, ATC-0175, SNAP-7941
Publisher: World Heritage Encyclopedia


Systematic (IUPAC) name
Clinical data
Routes of
CAS Registry Number
ATC code None
PubChem CID:
Chemical data
Formula C29H28F7NO2
Molecular mass 555.527 g/mol

Serlopitant (VPD-737) is a drug which acts as an NK1 receptor antagonist. It was assessed in clinical trials for the treatment of urinary incontinence and overactive bladder, but while it was superior to placebo it provided no advantage over existing approved drugs, and was not approved for further development.[1][2]

See also


  1. ^ Frenkl TL, Zhu H, Reiss T, Seltzer O, Rosenberg E, Green S. A multicenter, double-blind, randomized, placebo controlled trial of a neurokinin-1 receptor antagonist for overactive bladder. J Urol. 2010 Aug;184(2):616-22. doi: 10.1016/j.juro.2010.03.147 PMID 20639026
  2. ^ Payton S. Urinary incontinence: Neurokinin receptor antagonist inferior to tolterodine for OAB. Nature Reviews Urology 2010; 7:418. doi:10.1038/nrurol.2010.105

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