World Library  
Flag as Inappropriate
Email this Article

Technetium (99mTc) nofetumomab merpentan

Article Id: WHEBN0009818301
Reproduction Date:

Title: Technetium (99mTc) nofetumomab merpentan  
Author: World Heritage Encyclopedia
Language: English
Subject: Technetium compounds, List of drugs: Te, Intetumumab, Onartuzumab, Ecromeximab
Collection:
Publisher: World Heritage Encyclopedia
Publication
Date:
 

Technetium (99mTc) nofetumomab merpentan

Technetium (99mTc) nofetumomab merpentan?
Monoclonal antibody
Type Fab fragment
Source Mouse
Clinical data
Trade names Verluma
Pharmacokinetic data
Biological half-life 10.5 hours
Excretion renal (64%)
Identifiers
CAS Registry Number  N
ATC code None
 N   

Technetium (99mTc) nofetumomab merpentan (trade name Verluma) is a mouse monoclonal antibody used in the diagnosis of lung cancer,[1] gastrointestinal, breast, ovary, pancreas, kidney, cervix, and bladder carcinoma.[2] The antibody itself, nofetumomab, is attached to the chelator merpentan, which links it to the radioisotope technetium-99m (99mTc).[3]

References

  1. ^ Straka, MR; Joyce, JM; Myers, DT (2000). "Tc-99m nofetumomab merpentan complements an equivocal bone scan for detecting skeletal metastatic disease from lung cancer". Clinical nuclear medicine 25 (1): 54–5.  
  2. ^ Breitz, HB; Tyler, A; Bjorn, MJ; Lesley, T; Weiden, PL (1997). "Clinical experience with Tc-99m nofetumomab merpentan (Verluma) radioimmunoscintigraphy". Clinical nuclear medicine 22 (9): 615–20.  
  3. ^ WHO Drug Information


This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and USA.gov, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for USA.gov and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
 
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
 
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.
 


Copyright © World Library Foundation. All rights reserved. eBooks from Project Gutenberg are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.