Urb-597

URB597
Identifiers
CAS number 546141-08-6 N
PubChem 1383884
ChemSpider 1156960 YesY
MeSH URB597
Jmol-3D images Image 1
Properties
Molecular formula C20H22N2O3
Molar mass 338.4 g/mol
 N (verify) (what is: YesY/N?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

URB597 is a relatively selective inhibitor of the enzyme fatty acid amide hydrolase (FAAH).[1][2] FAAH is the primary degradatory enzyme for the endocannabinoid anandamide and, as such, inhibition of FAAH leads to an accumulation of anandamide in the CNS and periphery where it activates cannabinoid receptors. In pre-clinical laboratory tests researchers found URB597 increased the production of endocannabinoids resulting in measurable antidepressant and analgesic effects.[3]

URB597 is also known as KDS-4103. KDS-4103 is being developed by Kadmus Pharmaceuticals, Inc. for clinical trials in humans. Kadmus claims, on their website (linked below) that this class of compounds may have antidepressant, anti-anxiety, and pain-killing effects.

See also

  • 4-Nonylphenylboronic acid
  • LY-2183240
  • PF-04457845

References

External links

  • Kadmus Pharmaceuticals official website
  • Nature
  • New drug acts as marijuana in the brain at cannabis.net


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