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Title: Aclarubicin  
Author: World Heritage Encyclopedia
Language: English
Subject: Chemotherapy, Cell-cycle nonspecific antineoplastic agents, Hazardous drugs, Ortataxel, Triethylenemelamine
Publisher: World Heritage Encyclopedia


Systematic (IUPAC) name
(1S,2S,4R)-Methyl 4-(((2S,5R,6R)-4-(dimethylamino)-5-(((1S,3R,4S)-3-hydroxy-5-methyl-4-(((2S,6R)-6-methyl-5-oxotetrahydro-2H-pyran-2-yl)oxy)cyclohexyl)oxy)-6-methyltetrahydro-2H-pyran-2-yl)oxy)-2-ethyl-2,5,7-trihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracene-1-carboxylate
Clinical data
Legal status
  • Prescription only
Routes IV
CAS number  N
ATC code L01
ChemSpider  YesY
Chemical data
Formula C42H53NO15 
Mol. mass 811.86 g/mol

Aclarubicin (INN) or aclacinomycin A[1] is an anthracycline drug[2] that is used in the treatment of cancer. Soil bacteria Streptomyces galilaeus can produce aclarubicin.


  1. ^ PubChem 451415
  2. ^ Jensen PB, Jensen PS, Demant EJ, et al. (October 1991). "Antagonistic effect of aclarubicin on daunorubicin-induced cytotoxicity in human small cell lung cancer cells: relationship to DNA integrity and topoisomerase II". Cancer Res. 51 (19): 5093–9.  

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