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Title: Ccl3  
Author: World Heritage Encyclopedia
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Subject: Immunotherapy, Chemokine, Allergic conjunctivitis, CCR5, Chromosome 17 (human), Macrophage inflammatory protein, CCL4, CCL14, CCL18, CC chemokine receptors
Publisher: World Heritage Encyclopedia


For the aerodrome using the TC LID, CCL3, see Christina Lake Aerodrome.
Chemokine (C-C motif) ligand 3
PDB rendering based on 1b50.
Available structures
PDB Ortholog search: RCSB
CCL3 Gene
RNA expression pattern

Chemokine (C-C motif) ligand 3 (CCL3) is a protein that in humans is encoded by the CCL3 gene.

CCL3, also known as Macrophage inflammatory protein-1α (MIP-1α), is a cytokine belonging to the CC chemokine family that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes (Wolpe et al., 1988). Sherry et al. (1988) demonstrated 2 protein components of MIP1, called by them alpha and beta.[supplied by OMIM][1]


CCL3 has been shown to interact with CCL4.[2]

See also


Further reading

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