World Library  
Flag as Inappropriate
Email this Article

Cd276

Article Id: WHEBN0014819578
Reproduction Date:

Title: Cd276  
Author: World Heritage Encyclopedia
Language: English
Subject: CD153, CD109, IGSF2, LY75, NKG2
Collection:
Publisher: World Heritage Encyclopedia
Publication
Date:
 

Cd276

CD276 molecule
Identifiers
Symbols  ; 4Ig-B7-H3; B7-H3; B7H3; B7RP-2
External IDs GeneCards:
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)
PubMed search

CD276 (Cluster of Differentiation 276) is a human protein encoded by the CD276 gene.[1] Costimulatory B7 molecules (e.g., B7-1, or CD80; MIM 112203) signal through CD28 (MIM 186760) family molecules such as CD28, CTLA4 (MIM 123890), and ICOS (MIM 604558).[supplied by OMIM][1]

CD276 (aka B7-H3) is expressed by some solid tumours and is the target of anticancer candidates such as MGA271.[2]

See also

References

  1. ^ a b "Entrez Gene: CD276 CD276 molecule". 
  2. ^ http://www.genengnews.com/gen-news-highlights/servier-pays-macrogenics-20m-for-option-to-anticancer-antibody/81246017/

Further reading

External links

This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and USA.gov, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for USA.gov and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
 
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
 
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.
 


Copyright © World Library Foundation. All rights reserved. eBooks from Project Gutenberg are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.