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Title: Cxcl17  
Author: World Heritage Encyclopedia
Language: English
Subject: Outline of immunology, Cytokines, CXCL15, Proinflammatory cytokine, CXCL16
Publisher: World Heritage Encyclopedia


chemokine (C-X-C motif) ligand 7
Symbol CXCL17
Alt. symbols SCYB17, VCC-1, DMC
Entrez 284340
RefSeq NM_198477
UniProt Q6UXB2
Other data
Locus Chr. 19 q13.2

Chemokine (C-X-C motif) ligand 17 (CXCL17) is a small cytokine belonging to the CXC chemokine family that has been identified in humans and mice. CXCL17 attracts dendritic cells and monocytes and is regulated in tumors. It is also known as VEGF co-regulated chemokine 1 (VCC-1) and dendritic cell- and monocyte-attracting chemokine-like protein (DMC).[1][2] This chemokine is constitutively expressed in the lung.[2] The gene for human CXCL17 is located on chromosome 19.[2]


  1. ^ Weinstein E, Head R, Griggs D, Sun D, Evans R, Swearingen M, Westlin M, Mazzarella R (2006). "VCC-1, a novel chemokine, promotes tumor growth". Biochem Biophys Res Commun 350 (1): 74–81.  
  2. ^ a b c Pisabarro M, Leung B, Kwong M, Corpuz R, Frantz G, Chiang N, Vandlen R, Diehl L, Skelton N, Kim H, Eaton D, Schmidt K (2006). "Cutting edge: novel human dendritic cell- and monocyte-attracting chemokine-like protein identified by fold recognition methods". J Immunol 176 (4): 2069–73.  

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