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Title: Calgranulin  
Author: World Heritage Encyclopedia
Language: English
Subject: Kidney stone, Minor histocompatibility antigen, Synapsin 2, HLA-C, HLA-DRA
Publisher: World Heritage Encyclopedia


Calgranulin is an S100 calcium-binding protein that is expressed in multiple cell types, including renal epithelial cells and neutrophils.

The proteins S100A8 and S100A9 form a heterodimer called calprotectin.


  • Human genes 1
  • Function 2
  • References 3
  • See also 4
  • External links 5

Human genes


Some in vitro evidence suggests that calgranulin can inhibit the precipitation of calcium oxalate in a urine-like environment at calgranulin concentrations below physiological concentrations.[1] Thus, it may also function in vivo as an inhibitor of calcium oxalate kidney stone formation. However, the role of calgranulin in the stone formation process has not been evaluated.


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See also

External links

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