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Title: Clofedanol  
Author: World Heritage Encyclopedia
Language: English
Subject: ATC code R05, List of drugs: U
Publisher: World Heritage Encyclopedia



Clofedanol (INN) or chlophedianol (BAN) is a centrally-acting cough suppressant used in the treatment of dry cough. Clofedanol has local anesthetic and antihistamine properties, and may have anticholinergic effects at high doses.[1] It is marketed in Canada under the trade name Ulone, but is not available currently in the United States. In August 2009, Centrix Pharmaceutical announced the launch of a cough syrup containing a mixture of clophedianol and pseudoephedrine, marketed under the brand name Clofera. It has a release to market date in the beginning of the fourth quarter 2009.[2] Chlophedianol was approved for OTC status in 1987 by the FDA OTC monograph process[3] and its safety and efficacy data are limited.


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