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Title: Hla-dqa2  
Author: World Heritage Encyclopedia
Language: English
Subject: MHC class II
Publisher: World Heritage Encyclopedia


Major histocompatibility complex, class II, DQ alpha 2
RNA expression pattern

HLA class II histocompatibility antigen, DQ(6) alpha chain is a protein that in humans is encoded by the HLA-DQA2 gene. Also known as HLA-DXA or DAAP-381D23.2, it is part of the human leucocyte antigen system.[1]

The protein encoded by this gene is expressed, but unlike HLA-DQA1, it apparently unable to heterodimerize with HLA class II beta chain paralogues.[2] The low level of HLA-DQA2 expression is apparently due to impaired transcription factor binding to the HLA-DQA2 gene promoter.[3]


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