World Library  
Flag as Inappropriate
Email this Article

Relaxin receptor

Article Id: WHEBN0013252222
Reproduction Date:

Title: Relaxin receptor  
Author: World Heritage Encyclopedia
Language: English
Subject: List of human hormones
Publisher: World Heritage Encyclopedia

Relaxin receptor

relaxin/insulin-like family peptide receptor 1
Symbol RXFP1
Alt. symbols LGR7
Entrez HUGO OMIM RefSeq UniProt Locus q31.3
relaxin/insulin-like family peptide receptor 2
Symbol RXFP2
Alt. symbols LGR8, GREAT, GPR106, INSL3R
Entrez HUGO OMIM RefSeq UniProt Locus q12.3
relaxin/insulin-like family peptide receptor 3
Symbol RXFP3
Alt. symbols RLN3R1, SALPR, GPCR135
Entrez HUGO OMIM RefSeq UniProt Locus p15.1-p14
relaxin/insulin-like family peptide receptor 4
Symbol RXFP4
Alt. symbols GPR100, GPCR142, RLN3R2
Entrez HUGO OMIM RefSeq UniProt Locus q22

The relaxin receptors are a subclass of four closely related G protein-coupled receptors that bind relaxin peptide hormones.[1][2]

Below is list of human relaxin receptors, their endogenous peptide hormones, and what down stream enzymes are activated or inhibited by the receptor.

receptor/gene ligands activates inhibits
RXFP1 Relaxin 1, Relaxin 2, Relaxin 3 adenylate cyclase, protein kinase A, protein kinase C,

phosphatidylinositol 3-kinase, extracellular signal-regulated kinases (Erk1/2)

RXFP2 Relaxin 1, Relaxin 2, INSL3 adenylate cyclase
RXFP3 Relaxin 3 Erk1/2 signaling adenylate cyclase
RXFP4 Relaxin 3, INSL3 adenylate cyclase

See also

  • Relaxin family peptide hormones
  • Relaxin-3


External links

  • Medical Subject Headings (MeSH)
This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.

Copyright © World Library Foundation. All rights reserved. eBooks from Project Gutenberg are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.