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Skene's gland

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Title: Skene's gland  
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Subject: Vulva, Prostate, Anterior fornix erogenous zone, Bus (disambiguation), Sinus tubercle
Collection: Exocrine System, Glands, Mammal Female Reproductive System
Publisher: World Heritage Encyclopedia

Skene's gland

Skene's gland
Skene's gland opening is pictured.
Latin glandulae vestibulares minores
Urogenital sinus
Gray's p.1213
Paraurethral glands
Anatomical terminology

In human anatomy (female), Skene's glands or the Skene glands () (US dict: ) (also known as the lesser vestibular glands, periurethral glands, paraurethral glands,[1] female prostate) are glands located on the anterior wall of the vagina, around the lower end of the urethra. They drain into the urethra and near the urethral opening and may be near or a part of the G-spot. These glands are surrounded with tissue (which includes the part of the clitoris) that reaches up inside the vagina and swells with blood during sexual arousal.


  • Structure and function 1
  • Clinical significance 2
  • History 3
  • See also 4
  • References 5
  • External links 6

Structure and function

The location of the Skene's gland is the general area of the vulva, glands located on the anterior wall of the vagina around the lower end of the urethra. They are homologous with the prostate gland in males.[2] The Skene's ducts are a pair of ducts leading from the Skene's glands to the surface of the vulva, to the left and right of the urethral opening.

It has been postulated that the Skene's glands are the source of female ejaculation.[3] Female ejaculate, which may emerge during

  • Davì, G.; Asta, G.; Lagalla, R.; Midiri, M.; Mercadante, G. (1999). "Skene's gland pseudocysts. An occasional finding with computed tomography and ultrasound". La Radiologia medica 98 (4): 314–316.  
  • Radiology images of the Skene's gland
  • Jones N (3 July 2002). "Bigger is better when it comes to the G spot". New Scientist. 
  • Geddes L (20 February 2008). "Ultrasound nails location of the elusive G spot". New Scientist. 
  • Gravina GL, Brandetti F, Martini P, et al. (March 2008). "Measurement of the thickness of the urethrovaginal space in women with or without vaginal orgasm". J Sex Med 5 (3): 610–8.  

External links

  1. ^ "paraurethral glands" at Dorland's Medical Dictionary
  2. ^ Zaviacic M, Jakubovská V, Belosovic M, Breza J (2000). "Ultrastructure of the normal adult human female prostate gland (Skene's gland)". Anat Embryol (Berl) 201 (1): 51–61.  
  3. ^ Rabinerson D, Horowitz E (February 2007). "[G-spot and female ejaculation: fiction or reality?]". Harefuah (in Hebrew) 146 (2): 145–7, 163.  
  4. ^ Kratochvíl S (1994). "Orgasmic expulsions in women". Cesk Psychiatr 90 (2): 71–7.  
  5. ^ Wimpissinger, F.; Stifter, K.; Grin, W.; Stackl, W. (2007). "The Female Prostate Revisited: Perineal Ultrasound and Biochemical Studies of Female Ejaculate".  
  6. ^ Zaviacic, M; L Danihel, M Ruzicková, J Blazeková, Y Itoh, R Okutani, T Kawai. (March 1997). "Immunohistochemical localization of human protein 1 in the female prostate (Skene's gland) and the male prostate". Histochem J. 29 (3): 219–27.  
  7. ^ Nicola Jones (3 July 2002). "Bigger is better when it comes to the G-Spot". New Scientist. 
  8. ^ Zaviacic, Z; V Jakubovská, M Belosovic, J Breza. (January 2000). "Ultrastructure of the normal adult human female prostate gland (Skene's gland)". Anat Embryol (Berl). 201 (1): 51–61.  
  9. ^ Zaviacic, Z; M Ruzicková, J Jakubovský, L Danihel, P Babál, J Blazeková. (November 1994). "The significance of prostate markers in the orthology of the female prostate". Bratisl Lek Listy. 95 (11): 491–7.  
  10. ^ Wernert, N; M Albrech, I Sesterhenn, R Goebbels, H Bonkhoff, G Seitz, R Inniger, K Remberger. (1992). "The 'female prostate': location, morphology, immunohistochemical characteristics and significance". Eur Urol. 22 (1): 64–9.  
  11. ^ Tepper, SL; J Jagirdar, D Heath, SA Geller. (May 1984). "Homology between the female paraurethral (Skene's) glands and the prostate. Immunohistochemical demonstration". Arch Pathol Lab Med. 108 (5): 423–5.  
  12. ^ Pollen, JJ; A. Dreilinger (March 1984). "Immunohistochemical identification of prostatic acid phosphatase and prostate specific antigen in female periurethral glands". Urology. 23 (3): 303–4.  
  13. ^ Zaviacic, Z; RJ Ablin. (January 2000). "The female prostate and prostate-specific antigen. Immunohistochemical localization, implications of this prostate marker in women and reasons for using the term "prostate" in the human female". Histol Histopathol. 15 (1): 131–42.  
  14. ^ Jannini E, Simonelli C, Lenzi A (2002). "Sexological approach to ejaculatory dysfunction". Int J Androl 25 (6): 317–23.  
  15. ^ Jannini E, Simonelli C, Lenzi A (2002). "Disorders of ejaculation". J Endocrinol Invest 25 (11): 1006–19.  
  16. ^ Heath D (1984). "An investigation into the origins of a copious vaginal discharge during intercourse: "Enough to wet the bed" - that "is not urine"". J Sex Res. 20 (2): 194–215.  
  17. ^ Chalker, Rebecca (2002). The Clitoral Truth: The secret world at your fingertips. New York: Seven Stories.  
  18. ^ Miranda EP, Almeida DC, Parente JM, Ribeiro GP, Scafuri AG (2008). "Surgical Treatment for Recurrent Refractory Skenitis". TheScientificWorldJOURNAL 8: 658–660.  
  19. ^ Gittes, RF Nakamura RM (May 1996). "Female urethral syndrome. A female prostatitis?". Western Journal of Medicine 164 (5): 435–438.  
  20. ^ S. Gene McNeeley, MD (December 2008). "Skene's duct cyst". Merck Manuals Online Medical Library. Merck. Retrieved 5 March 2010. 
  21. ^ Skene's glands at Who Named It?
  22. ^ Skene A (1880). "The anatomy and pathology of two important glands of the female urethra". Am J Obs Dis Women Child 13: 265–70. 
  23. ^ synd/2037 at Who Named It?


See also

While the glands were first described by the French surgeon Alphonse Guérin (1816-1895), they were named after the Scottish gynaecologist Alexander Skene, who wrote about it in Western medical literature in 1880.[21][22][23]


  • Skene's duct cyst[20]
A Skene's duct cyst, pressing the urethral opening towards the right side of the image.

Disorders of or related to the Skene's gland include:

Clinical significance

It has been demonstrated that a large amount of fluid can be secreted from this gland when stimulated from inside the vagina.[16] Some reports indicate that embarrassment regarding female ejaculation, and the debated notion that the substance is urine, can lead to purposeful suppression of sexual climax, leading women to seek medical advice and even undergo surgery to "stop the urine".[17]

[15][14] In 2002, Emanuele Jannini of

[13] and are referring to it instead as the female prostate.Skene's gland Because they are increasingly perceived as merely different versions of the same gland, some researchers are moving away from the term [12][11][10][9] studies.prostatic acid phosphatase and prostate-specific antigen and both act similarly in terms of [8] When examined with electron microscopy, both glands show similar secretory structures,[7] where women without the gland had lower concentrations.PDE5 and the enzyme [6]human urinary protein 1 containing biochemical markers of sexual function like [5][4]

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