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Tmc1

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Subject: Chromosome 9 (human), Nonsyndromic deafness
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Tmc1

Transmembrane channel-like 1
Identifiers
TMC1 Gene
RNA expression pattern

Transmembrane channel-like protein 1 is a protein that in humans is encoded by the TMC1 gene.[1][2][3]

Function

This gene is considered a member of a gene family predicted to encode transmembrane proteins. The specific function of this gene is unknown; however, it is known to be required for normal function of cochlear hair cells.[3]

Clinical significance

Mutations in this gene have been associated with progressive postlingual hearing loss and profound prelingual deafness.[3]

References

Further reading

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