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Adam2

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Title: Adam2  
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Subject: TI-AR7, Pregnancy-associated plasma protein A, ADAM17, Firmware, ADAM8
Collection: Human Proteins, Peptidase
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Adam2

ADAM metallopeptidase domain 2
Identifiers
Symbols  ; CRYN1; CRYN2; CT15; FTNB; PH-30b; PH30; PH30-beta
External IDs GeneCards:
RNA expression pattern
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)
RefSeq (protein)
Location (UCSC)
PubMed search

Disintegrin and metalloproteinase domain-containing protein 2 is an enzyme that in humans is encoded by the ADAM2 gene.[1][2][3] This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This member is a subunit of an integral sperm membrane glycoprotein called fertilin, which plays an important role in sperm-egg interactions.[3]

References

  1. ^
  2. ^
  3. ^ a b

Further reading

External links

  • The MEROPS online database for peptidases and their inhibitors: M12.950


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