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Title: Abetimus  
Author: World Heritage Encyclopedia
Language: English
Subject: Immunosuppressants, Atorolimumab, Maslimomab, ATC code L04, Aselizumab
Collection: Immunosuppressants
Publisher: World Heritage Encyclopedia


Clinical data
Legal status
CAS number  N
ATC code L04
Chemical data
Formula ?

Abetimus is an immunosuppressant.[1] It is a synthetic biological called a tolerogen. It is made of four double-stranded oligodeoxyribonucleotides that are attached to a carrier platform and are designed to block specific B-cell anti double stranded DNA antibodies.[2] It may also complex anti dsDNA antibodies together, therefore disabling them. This way Abetimus is supposed to help treat Systemic Lupus Erythematosus and specifically nephritis.


  1. ^ (not listed) (2003). "Abetimus: Abetimus sodium, LJP 394". BioDrugs (Adis) 17 (3): 212–215.  
  2. ^ Wallace, Daniel J. (January 2001), "Clinical and pharmacological experience with LJP-394", Expert Opinion on Investigational Drugs (Informa) 10 (1): 111–117,  
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