World Library  
Flag as Inappropriate
Email this Article

Abetimus

Article Id: WHEBN0018828059
Reproduction Date:

Title: Abetimus  
Author: World Heritage Encyclopedia
Language: English
Subject: Immunosuppressants, Atorolimumab, Maslimomab, ATC code L04, Aselizumab
Collection: Immunosuppressants
Publisher: World Heritage Encyclopedia
Publication
Date:
 

Abetimus

Abetimus
Clinical data
Legal status
?
Identifiers
CAS number  N
ATC code L04
Chemical data
Formula ?
 N   

Abetimus is an immunosuppressant.[1] It is a synthetic biological called a tolerogen. It is made of four double-stranded oligodeoxyribonucleotides that are attached to a carrier platform and are designed to block specific B-cell anti double stranded DNA antibodies.[2] It may also complex anti dsDNA antibodies together, therefore disabling them. This way Abetimus is supposed to help treat Systemic Lupus Erythematosus and specifically nephritis.

References

  1. ^ (not listed) (2003). "Abetimus: Abetimus sodium, LJP 394". BioDrugs (Adis) 17 (3): 212–215.  
  2. ^ Wallace, Daniel J. (January 2001), "Clinical and pharmacological experience with LJP-394", Expert Opinion on Investigational Drugs (Informa) 10 (1): 111–117,  
This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and USA.gov, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for USA.gov and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
 
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
 
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.
 


Copyright © World Library Foundation. All rights reserved. eBooks from Project Gutenberg are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.