World Library  
Flag as Inappropriate
Email this Article

Chemical modification

Article Id: WHEBN0006661744
Reproduction Date:

Title: Chemical modification  
Author: World Heritage Encyclopedia
Language: English
Subject: Protein structure, Circular dichroism, Prp24, Chemically modified electrode, Size-exclusion chromatography
Collection: Protein Structure
Publisher: World Heritage Encyclopedia

Chemical modification


  • Chemical modification in chemistry 1
  • Chemically modified electrodes 2
  • Chemical modification in biochemistry 3
    • Chemical modification of protein side chains 3.1
  • Chemical modification of nucleic acids 4
  • References 5

Chemical modification in chemistry

Chemically modified electrodes

Chemically modified electrodes are electrodes that have their surfaces chemically modified to change the electrode's physical, chemical, electrochemical, optical, electrical, and transport properties. These electrodes are used for advanced purposes in research and investigation.[1]

Chemical modification in biochemistry

In biochemistry, chemical modification is the technique of chemically reacting a protein or nucleic acid with chemical reagents. Chemical modification can have several goals, such as

  • to identify which parts of the molecule are exposed to solvent ("foot printing");
  • to determine which residues are important for a particular phenotype, e.g., which residues are important for an enzymatic activity;
  • to introduce new groups into a macromolecule; and
  • to crosslink macromolecules intra- and intermolecularly.

Chemical modification of protein side chains

Chemical modification of nucleic acids


  1. ^ Durst, R., Baumner, A., Murray, R., Buck, R., & Andrieux, C., "Chemically modified electrodes: Recommended terminology and definitions (PDF)", IUPAC, 1997, pp 1317–1323.

This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.

Copyright © World Library Foundation. All rights reserved. eBooks from Project Gutenberg are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.