World Library  
Flag as Inappropriate
Email this Article

Cochrane Library

The Cochrane Library (named after systematic reviews and meta-analyses which summarize and interpret the results of medical research. The Cochrane Library aims to make the results of well-conducted controlled trials readily available and is a key resource in evidence-based medicine.


  • Access and use 1
  • Contents 2
  • Format 3
  • Impact factor and ranking 4
  • Academic comments 5
  • References 6
  • External links 7

Access and use

The Cochrane Library is a subscription-based database, originally published by Update Software and now published by John Wiley & Sons, Ltd as part of Wiley Online Library. In many countries, including parts of Canada, the United Kingdom, Ireland, the Scandinavian countries, New Zealand, Australia, India, South Africa, and Poland, it has been made available free to all residents by "national provision" (typically a government or Department of Health pays for the license). There are also arrangements for free access in much of Latin America and in "low-income countries", typically via HINARI. All countries have free access to two-page abstracts of all Cochrane Reviews and to short plain-language summaries of selected articles.[1]

Cochrane Reviews appear to be relatively underused in the United States, presumably because public access is limited (the state of Wyoming is an exception, having paid for a licence to enable free access to Cochrane Reviews for all residents of Wyoming).[2]


The Cochrane Library consists of the following databases:

  • The Cochrane Database of Systematic Reviews (Cochrane Reviews). Contains all the peer-reviewed systematic reviews and protocols prepared by the Cochrane Review Groups.
  • The Database of Abstracts of Reviews of Effects (DARE). Contains quality-assessed abstracts of systematic reviews, including a summary of the review and a critical appraisal of its overall quality.
  • The Cochrane Central Register of Controlled Trials (CENTRAL). Is a database that contains details of articles of Controlled trials and other studies of healthcare interventions from bibliographic databases (majorly MEDLINE and EMBASE), and other published and unpublished sources that are difficult to access.[3]
  • The Cochrane Methodology Register (Methodology Register). Is a bibliography of publications that report on methods used in the conduct of controlled trials.
  • Health Technology Assessment Database (HTA). Brings together details of completed and ongoing health technology assessments (studies of the medical, social, ethical and economic implications of healthcare interventions) from around the world.
  • NHS Economic Evaluation Database (NHS EED). This database systematically identifies economic evaluations from around the world, appraises their quality, and highlights their relative strengths and weaknesses.[4]

The Cochrane Reviews, CENTRAL, Methodology Reviews and Methodology Register are produced by the Cochrane Collaboration. DARE, HTA and NHS EED are compiled and maintained by the Centre for Reviews and Dissemination.


Cochrane Reviews take the format of full-length methodological studies. Cochrane researchers will perform searches of medical databases including MEDLINE, PubMed and EMBASE; a continually updated database of trials called the Cochrane Central Register of Controlled Trials (CENTRAL); hand searching, where researchers look through entire libraries of scientific journals by hand and; reference checking of obtained articles in order to identify studies that are relevant to the question they are attempting to answer.

The quality of each study is carefully assessed using predefined criteria and evidence of weak methodology or the possibility that a study may have been affected by bias is reported in the review.

Cochrane Researchers then apply statistical analysis to compare the data of the trials. This creates a review of studies, or systematic review, which gives the final word on the efficacy of a particular medical intervention. The result often shows a lack of evidence for a particular treatment one way or the other, recommending additional medical studies before doctors and pharmacists prescribe a particular intervention.

Finished reviews are available as a full report with diagrams, in condensed form or as a plain language summary, in order to provide for every reader of the review.[5]

Impact factor and ranking

In the most recent Journal Citation Reports publication, The Cochrane Database of Systematic Reviews has a 2010 impact factor of 6.186, ranking it 10th among 151 journals in the category "Medicine, General & Internal".

Academic comments

The Cochrane Library Feedback tool allows users to provide comments on and feedback of Cochrane Reviews and Protocols in The Cochrane Library. If accepted, the feedback will be published in a scrolling list of comments in reverse chronological order, with the most recent submission at the top of the page.[6] The Collaboration has a procedure for the event of serious error, an event which has only occurred once in its history.[7]


  1. ^ "Access options for the Cochrane Library". Cochrane Library. John Wiley & Sons, Inc. Retrieved 7 September 2015. 
  2. ^ Grimes DA, Hou MY, Lopez LM, Nanda K (February 2008). "Do clinical experts rely on the Cochrane library?". Obstet Gynecol 111 (2 Pt 1): 420–2.  
  3. ^ Dickersin K, Manheimer E, Wieland S, Robinson KA, Lefebvre C, McDonald S. Development of the Cochrane Collaboration’s Central Register of Controlled Clinical Trials. Eval Health Prof. 2002 Mar 1;25(1):38–64.
  4. ^ "About The Cochrane Library". The Cochrane Library. Retrieved 2012-11-29. 
  5. ^ "Newcomer’s guide". Cochrane Library. Retrieved 2010-11-29. 
  6. ^ The Cochrane Collaboration. The Cochrane Manual Issue 1, 2008, section COCHRANE LIBRARY FEEDBACK HOUSE RULES [updated 15 November 2007]. ( (accessed 12 December 2007)
  7. ^ Process in the event of serious errors in published Cochrane Reviews

External links

  • The Cochrane Library on Wiley Online
  • Abstracts and summaries of Cochrane Reviews, free access
  • , 1988-2003The Cochrane LibraryThe evolution of
  • The Centre for Reviews and Dissemination
This article was sourced from Creative Commons Attribution-ShareAlike License; additional terms may apply. World Heritage Encyclopedia content is assembled from numerous content providers, Open Access Publishing, and in compliance with The Fair Access to Science and Technology Research Act (FASTR), Wikimedia Foundation, Inc., Public Library of Science, The Encyclopedia of Life, Open Book Publishers (OBP), PubMed, U.S. National Library of Medicine, National Center for Biotechnology Information, U.S. National Library of Medicine, National Institutes of Health (NIH), U.S. Department of Health & Human Services, and, which sources content from all federal, state, local, tribal, and territorial government publication portals (.gov, .mil, .edu). Funding for and content contributors is made possible from the U.S. Congress, E-Government Act of 2002.
Crowd sourced content that is contributed to World Heritage Encyclopedia is peer reviewed and edited by our editorial staff to ensure quality scholarly research articles.
By using this site, you agree to the Terms of Use and Privacy Policy. World Heritage Encyclopedia™ is a registered trademark of the World Public Library Association, a non-profit organization.

Copyright © World Library Foundation. All rights reserved. eBooks from Project Gutenberg are sponsored by the World Library Foundation,
a 501c(4) Member's Support Non-Profit Organization, and is NOT affiliated with any governmental agency or department.